Members of the Adams Lab

Erin Adams

Principal Investigator and Mentor

Erin loves to figure out how things work both in and outside the lab.
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She loves being a mom and living on the South Side. She has been at the University of Chicago since 2005.

ejadams-at-uchicago.edu

Lab Manager

Sophie Krahnke

Lab Manager and Keeper Straight of Everything

Sophie is the lab manager and spends much of her time making sure the lab runs like a well-oiled machine! Research-wise, she is interested in the class I MHC molecule HLA-F and its role in the immune system, particularly in the context of viral infections and cancer.

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Outside of the lab, you can find Sophie running, baking, singing, and bingeing true crime podcasts.

Postdocs/Research Associates

Caitlin Castro

Research Associate

pronouns: she/her
Caitlin is examining the role of CD1d-reactive gamma delta (γδ) T cells in human diseases. She is specifically interested in the prevalence, in vivo significance, and functional characteristics of these cells in colorectal tumors. She is also studying the structure and function of γδ T cell receptors in sharks.
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In her free time Caitlin enjoys reading, playing banjo, and going on long (but not too fast) bike rides.

Charlotte James

Postdoc

Charlotte is interested in the molecular mechanisms that govern T cell recognition of MHC Class I-like molecules and elucidating the functional role of nonclassical T cells in human disease processes.
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Outside of the lab, she enjoys gardening, swimming, and learning new crafts.

Kristof Nolan

Postdoc

Kristof is working on understanding how unique NK cell receptors function to recognize unique ligands and MHC-related molecules during homeostasis and in various disease-state pathologies such as cancer. He is working to understand these interactions through biochemical, structural, and cellular-based approaches.
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When Kristof is not in lab, he enjoys practicing Brazilian jiujitsu, playing piano, and spending time with his wife and dog.

Sobhan Roy

Research Associate

Sobhan’s research is focused on classical and non-classical major histocompatibility complex (MHC) molecules and their recognition by αβ and γδ T cells. He is using immunological, crystallographic, and biochemical techniques to understand the molecular basis of antigen presentation and its recognition by T cell receptors in the context of pathogenic infection and cancer.
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Besides lab, Sobhan likes to play and watch cricket in his free time, listen to music, read books, watch movies, and try new recipes.

Graduate Students

Augusta Broughton

Grad Student (COI)

Augusta is interested in studying the role of tissue resident Vδ1 T cells in homeostasis and disease.

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Augusta likes naps, nonfiction, and drumming.

Ryan Duncombe

Grad Student (COI)

Ryan studies mechanisms of self-antigen recognition by regulatory T cells in the hopes of better understanding their development and function.
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Ryan’s favorite hobbies include reading, spending time outdoors no matter the weather, and running triathlons very slowly.

Nicole (Cole) Ladd

Grad Student (BMB)

pronouns: she/her
Cole is interested in the mechanism of antigen presentation by the MHC-like molecule MR1 and the structural features governing antigen discrimination by MR1-restricted TCRs
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In her free time, you can find her attending musicals, bouldering, crocheting, and reading.

laddna-at-uchicago.edu

Twitter

Sofi Maltseva

Visiting Grad Student (Ka Yee Lee Lab, Chem)

Sofi is a member of Prof. Ka Yee Lee’s group in Chemistry. She is interested in identifying lipid parameters that affect recognition of target membranes by alpha-synuclein and the TIM family of proteins.

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In her free time, Sofi enjoys piano, basketball, and painting.

Amrita Ramesh

MSTP Grad Student (BMB)

Amrita is interested in the mechanism by which Vγ9Vδ2 T cells activate in response to malignancy and infection.

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Between experiments, Amrita prefers to always be outside backpacking, picnicking by the lake, or attending music festivals.

Philipp Ross

Grad Student (GGSB)

pronouns: he/him

Philipp works on the molecular mechanisms of self versus non-self recognition at the maternal-fetal interface in humans and non-human primates. Prior to joining the Adams Lab, he worked as a bioinformatician in the Llinás Lab on transcriptional regulation in Plasmodium falciparum.

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Outside of the lab, he enjoys listening to and playing a variety of music and staying fit, mostly through running.

Twitter

Sean Ryan

Grad Student (COI)

Sean spends his time in lab exploring the importance of the MR1-T cell axis and its relevance to certain cancers.

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Outside of lab you can find him rock climbing, exploring restaurants in Chicago, or at home reading a science fiction novel.

Mayuri Viswanathan

MSTP Grad Student (COI)

Mayuri studies the role of γδ T cells in multiple sclerosis pathogenesis. She is particularly interested in characterizing the role of antigen specific brain resident gamma deltas using microscopy and sequencing techniques.

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She loves dogs, books, and sunshine, and spends her free time dancing and riding her bike along the Lakefront Trail.

Undergraduate Researchers

Tala Azzam

Biochemisty

Tala is studying the structure and antigen presentation of a non-classical MHC molecule in Xenopus.

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Outside of the lab, Tala enjoys rowing and long road trips.

Andrew Peev

Biology

Andrew investigates the structural flexibility of MR1 and its binding modes using computational modeling methods.

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Outside of lab, he is involved in UCEMS and UChicago Road Runners.

Daniel Yong

Biology

Daniel is a fourth year undergraduate student majoring in Biology. His current research focus is on HLA-B73.

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In his free time, he enjoys collecting fountain pens and dancing.

Lab Mascots

Spumante

Bebe

Dinosaur Master

Capt’n Jack

Rosalind

Oliver

Rosie

Hemera

Finnegan

Mia (Mimi) Brottsegen

Sabine

Xena

Lab Alumni

Are you an Adams Lab Alumna or Alumnus and don’t see your name below or your status is out of date? Contact us to check in and give us an update.

Postdoc Alumni

Cara Froyd, PhD (2013-2018), Scientist, Creative Communications and Media
John Leonard, PhD (2014-2018), Senior Scientist, 3T Biosciences
Adrienne Luoma, PhD (2014-2016), Postdoc @ Harvard
Andrew Sandstrom, PhD (2014), Assistant Professor, UT Southwestern
Jacinto Lopez-Sagaseta, PhD (2009-2014), Head, Protein Crystallography, Navarrabiomed
Aparna Palakodeti, PhD (2009-2011), Adjunct Faculty, College of DuPage
Kajal Chourdhary, PhD (2007-2008), Senior Manager, Reproductive Health Strategies, Takara Bio USA, Inc.

Graduate Student Alumni

Chris Boughter PhD (2021), Postdoc in the Meier_Schellersheim Lab @ NIH
Marta Borowska PhD (2020), Postdoc in the Garcia Lab @ Stanford
Ramya Parameswaran PhD,MD (2018), MSTP, University of Chicago
May Gu PhD (2018), Postdoc in Handel lab, UC San Diego
Charlie Dulburger, PhD (2017), Postdoc in Rubin lab, Harvard
James Crooks, PhD (2015), Senior Software Engineer, Facebook
Adrienne Luoma, PhD (2014), Postdoc in Wucherpfennig lab, Harvard
Andrew Sandstrom, PhD (2014), Assistant Professor, UT Southwestern
Greg Tietjen, PhD (2013), Assistant Professor, Surgery: Transplant & Immunology, Yale
Caitlyn Yeykal, PhD (2012), Global Project Management at Merck
Louise Scharf, PhD (2010), Scientist II, 23andMe

Masters Alumni

Zuzanna Kotkowska (2017), pursuing PhD at University Hospital Zurich
Wioletta Nawrocka (2015), pursuing PhD at University of Chicago
Agata Oruba (2008), Senior Scientist at Avacta
Filip Golebiowski (2007), Business Analyst, Roche

Undergraduate Alumni

Sam Dubensky (2016-2019), MD-PhD Student, Perelman School of Medicine at the University of Pennsylvania
Natalie Gray (2016-2018), Physics Teacher, Great Hearts Academies
Mary Coomes (2015-2017), Medical student
Ady Steinbach (2014-2017), pursuing PhD at UCSF
Victor Liu (2012-2014), pursuing Medical degree at University of Texas Houston
Carissa Lim (2013-2015)
Joel Siegel (2012-2013)
Irvin Ho (2011-2012)
Jenifer Kung (2010-2012), Postdoc at Genetech
Lakshmi Sundaresan (2010-2012), Resident, Rush University Medical School
Allison Kazen (Thoburn) (2006-2010), MD, Geriatric Medicine
Steve Mudroch (2009-2010), MD, Internal Medicine
Allison Roberts (2006-2008), Postdoc, Cox Lab UCBerkeley
Wesley Jun (2006-2007), Product Transfer Scientist @ Cepheid

Undergraduate Research Visiting Summer Student Alumni

Leah Sibener (Summer 2010)
Sneha Shah (Summer 2009)
Heather Lavezzi (Summer 2008)
Valentina Dimitrova (Summer 2008)
John Haughner (Summer 2007)
Hoa B Nguyen (Summer 2006)

University of Chicago Post-Baccalaureate Research Education Program (PREP) Alumni

Natassia Buckridge (2015)
Gabrielle McRae (2011)

Lab Manager Alumni

Leslie Bembinster (2013-2016) Model, Scientist, Model-Scientist, Very Cool-Person. See her Interview article
Chelsea Parks (2011-2013) Executive Chef at National Instruments, Austin